Unleashing the Power of Genomic Sequencing: MGI's DNBSEQ™ Technology Revolution

In the dynamic field of genomic sequencing, MGI's DNBSEQ™ technology stands as a groundbreaking innovation, redefining efficiency, accuracy, and versatility in genetic research. This cutting-edge technology, integrated with MGI's advanced sequencing platforms and reagents, is revolutionizing genomic studies and research applications.

Introducing DNBSEQ™ Technology: A Milestone in Genomic Accuracy

MGI's DNBSEQ™ technology represents a significant leap in sequencing precision. Unlike traditional methods that rely on double-stranded linear DNA, DNBSEQ™ utilizes single-stranded DNA libraries. The core of this technology transforms single-stranded circular DNA into unique woolen ball-like structures, known as DNB nanoballs (DNBs). This transformation occurs through a specialized process called rolling circle replication, a method that sets DNBSEQ™ apart in the sequencing field.

Enhanced Features of DNBSEQ™:

• Reduced Amplification Errors: The controlled enzymatic reaction intrinsic to rolling circle replication in DNBSEQ™ technology substantially minimizes amplification errors.

• Unmatched Fidelity: DNBSEQ™ employs an enzyme with the highest known fidelity, ensuring precise and accurate replication of the original DNA template.

• Prevention of Index Hopping: A critical advantage of DNBSEQ™ is its substantial reduction in index hopping rates, enhancing sample identification accuracy and utilization.

• Superior Sensitivity in SNP and Indel Detection: DNBSEQ™ technology brings heightened accuracy and sensitivity to the detection of single nucleotide polymorphisms (SNPs) and insertions/deletions (indels).

MGI's Sequencing Solutions: DNBSEQ™ T7 and DNBSEQ™ G400 Platforms

The DNBSEQ™ T7 and DNBSEQ™ G400 are key pillars of MGI's sequencing ecosystem, embodying the innovative spirit of DNBSEQ™ technology.

DNBSEQ™ T7: High-Speed and High-Throughput Sequencing

• Rapid Sequencing: The DNBSEQ™ T7 can complete a paired-end (PE) 100 sequencing run in a mere 22 hours, positioning it as one of the fastest sequencers available.

• User-Oriented Design: It offers the flexibility to operate between one to four flow cells simultaneously and boasts a user-friendly touchscreen interface.

• Impressive Data Production: The T7 can generate 1 to 4 terabases per day, with a single flow cell producing approximately 5,000 million reads.