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SpaTial Enhanced REsolution Omics-sequencing New Frontiers of Spatial Multi-omics

16 août 2023
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Speakers,

:

Dr. Jan Mulder

,

Dr. Yen-Yu Lin

SpaTial Enhanced REsolution Omics-sequencing New Frontiers of Spatial Multi-omics
SpaTial Enhanced REsolution Omics-sequencing New Frontiers of Spatial Multi-omics
SpaTial Enhanced REsolution Omics-sequencing New Frontiers of Spatial Multi-omics

SpaTial Enhanced REsolution Omics-sequencing New Frontiers of Spatial Multi-omics

Dive deep into the dynamic world of spatial multi-omics as we explore its revolutionary applications in genomics research. This blog post, inspired by discussions with industry experts, focuses on the latest advancements in spatial transcriptomics and their significant impact on scientific and clinical research.

The Revolutionary Technology of Spatial Enhanced Resolution Omic Sequencing

Spatial enhanced resolution omic sequencing represents a major leap in genomic science. This state-of-the-art technology facilitates an in-depth exploration of biological complexities, revolutionizing how researchers understand the spatial-temporal dimensions of biology.

Key Features and Applications:

  • High Resolution and Accuracy: This technology sets a new standard in spatial transcriptomics, offering unmatched precision. Its capability to detect the smallest nuances in biological samples is unparalleled.

  • Versatility in Sample Types: Its application extends beyond human tissues to plant tissues, making it a versatile asset in various fields of biological research.

  • 3D Reconstruction and Cell Segmentation: Offering 3D reconstruction and detailed cell segmentation analysis, this technology provides critical insights into the spatial organization within cells and tissues.

Integration of Stereoseq and MGI Sequencing Products

The combination of Stereoseq with MGI sequencing technologies, like the G400 and T7 sequencers, marks a significant advancement in spatial omics. This synergy enhances the capabilities of spatial multi-omics research.

DNBSEQ-T7
DNBSEQ-T7
DNBSEQ-T7

DNBSEQ-T7

Pioneering Precision in Spatial Multi-Omics

MGI's DNBSEQ-T7 is a transformative force in spatial enhanced resolution omic sequencing. Excelling in accuracy and efficiency, it complements Stereoseq's high-resolution capabilities in spatial transcriptomics. Ideal for intricate genomic research, the DNBSEQ-T7 is instrumental in deepening our understanding of biological systems and advancing studies in neurodegenerative diseases like frontotemporal dementia, marking a new era in genomic exploration.

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These MGI sequencers, when used in conjunction with Stereoseq, optimize DNA nanoball (DNB) sequencing technology. This integration minimizes amplification errors and index hopping, ensuring high-quality sequencing outcomes.

Advancing Human Protein Research through Spatial Transcriptomics

Spatial transcriptomics is pioneering new methodologies in understanding protein distribution, particularly in brain research. This approach offers a more nuanced view of protein expression, pivotal in the study of complex biological systems.

Breakthroughs in Disease Research:

  • Frontotemporal Dementia Studies: The use of spatial transcriptomics in neurodegenerative disease research, like frontotemporal dementia, showcases its potential in unraveling the complexities of these conditions.

  • Enhanced Data Analysis: This technology's ability to deliver cellular-level visualizations and analyses opens new paths for understanding the mechanisms behind various brain disorders and diseases.

The Impact of MGI Sequencing in Spatial Multi-Omics

MGI's sequencing technology plays a vital role in advancing spatial multi-omics. The G400 and G7 sequencers, in particular, have become instrumental in driving forward genomic and proteomic studies. Their compatibility with spatial transcriptomics tools like Stereoseq enhances the accuracy and detail of research outcomes.

MGI's Role in Spatial Genomics:

  • Innovation in Sequencing Technology: MGI's sequencing solutions, with their precision and efficiency, are at the forefront of genomic research.

  • Enhancing Research Capabilities: The integration of MGI sequencing products with spatial transcriptomics tools broadens the scope of research, facilitating more comprehensive studies in various fields.

Conclusion

The advancements in spatial enhanced resolution omic sequencing, particularly when combined with MGI's sequencing technologies, represent a significant stride in multi-omics research. These developments are not just reshaping our understanding of genomics and proteomics but also paving the way for groundbreaking discoveries in understanding complex biological systems. Spatial transcriptomics, especially in the context of brain research and neurodegenerative diseases, stands at the cusp of revolutionizing our approach to scientific exploration.

Disclaimer: The information provided in this blog is for educational and informational purposes only and is not intended for use in diagnostic procedures. MGI products mentioned are for research use only.

DNBSEQ-G400
DNBSEQ-G400
DNBSEQ-G400

DNBSEQ-G400

Harmonizing Spatial Insights with Stereoseq Excellence

The DNBSEQ-G400 by MGI is a cornerstone in the evolution of genomic studies, especially in the domain of spatial transcriptomics. This sequencer, known for its robustness and adaptability, is harmoniously compatible with Stereoseq, delivering high-resolution genomic insights. It's an invaluable asset in projects like the Human Protein Atlas, offering precise data visualization and analysis that are vital for understanding complex protein distributions and neurological disorders.

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Speakers

Dr. Jan Mulder - Group leader @Karolinska Institute
Dr. Jan Mulder - Group leader @Karolinska Institute
Dr. Jan Mulder - Group leader @Karolinska Institute

Dr. Jan Mulder

Group leader @Karolinska Institute

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Dr. Yen-Yu Lin - Senior field application scientist @BGI Research
Dr. Yen-Yu Lin - Senior field application scientist @BGI Research
Dr. Yen-Yu Lin - Senior field application scientist @BGI Research

Dr. Yen-Yu Lin

Senior field application scientist @BGI Research

Visit Company site

Stero-seq

Stereo Sequencing

Genomic Medicine

Neurodegenerative Disease Research

Human Protein Atlas

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Copyright © 2024 MGI tech GmbH, Ltd. All Rights Reserved.

Genomics Unlocked Background

Join our newsletter to stay up to date on our latest webinars.

Copyright © 2024 MGI tech GmbH, Ltd. All Rights Reserved.