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Comprehensive Molecular Tumor Analysis (CMTA) Integrating RNAseq and TME for Targeted Therapy

Sep 20, 2023
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Speakers,

:

Dr. Marie-Laure Yaspo

,

Priyanka Kurapati

Comprehensive Molecular Tumor Analysis (CMTA) integrating RNAseq and TME for targeted therapy
Comprehensive Molecular Tumor Analysis (CMTA) integrating RNAseq and TME for targeted therapy
Comprehensive Molecular Tumor Analysis (CMTA) integrating RNAseq and TME for targeted therapy

Comprehensive Molecular Tumor Analysis (CMTA) Integrating RNAseq and TME for Targeted Therapy

The landscape of cancer diagnosis and treatment is rapidly evolving, with precision oncology standing as a beacon of hope. This field's progress is largely driven by the integration of RNA sequencing (RNA-seq) and tumor microenvironment (TME) analysis through Comprehensive Molecular Tumor Analysis (CMTA). This blog will explore the significance of CMTA in cancer diagnostics and the critical role of MGI sequencers like the DNBSEQ G400, DNBSEQ G99, and DNBSEQ T7.

Understanding Comprehensive Molecular Tumor Analysis (CMTA)

CMTA marks a paradigm shift in cancer diagnostics, offering a holistic view of a patient's tumor biology. It integrates exome sequencing with transcriptome analysis, maximizing the chances of identifying actionable targets for personalized therapies.

Key Advantages of CMTA

  1. Maximizing Treatment Options: CMTA uncovers a wide range of mutations and alterations to guide targeted therapy selection.

  2. Personalized Therapy: Tailors treatments to each patient's unique tumor profile.

  3. Inclusion of Rare Cancers: Offers new possibilities for rare cancers and pediatric cases.

  4. Metastatic and Refractory Cancers: Unearths complex genetic abnormalities in advanced stages.

  5. Clinical Trial Enrollment: Assists in matching patients with relevant clinical trials.

MGI Sequencers: Empowering Comprehensive Molecular Tumor Analysis

MGI sequencers are crucial for realizing the full potential of CMTA, offering advanced solutions for both exome sequencing and transcriptome analysis.


  • DNBSEQ G400Versatility and Quality: Ideal for routine clinical use, with fast sequencing and high-quality output.

  • DNBSEQ G99 Speed and Efficiency: Renowned for its rapid sequencing capabilities, enhancing clinical workflows.

  • DNBSEQ T7 Scalability and Precision: Features increased throughput and precise sequencing data.

DNBSEQ-G99

DNBSEQ-G99

Transforming Cancer Diagnostics with CMTA

MGI's DNBSEQ-G99 is a pivotal instrument in cancer research, particularly in Comprehensive Molecular Tumor Analysis (CMTA). With its rapid sequencing capabilities, the G99 enhances the efficiency of RNA-seq and TME analysis, contributing significantly to personalized therapy planning and expanding treatment options for rare and advanced-stage cancers.



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How MGI Sequencers Enhance CMTA

MGI sequencers bring cost-effectiveness and high-quality data output to CMTA, making comprehensive profiling more accessible.

  • Cost-Effective Comprehensive Profiling: Enables larger-scale studies to discover rare alterations.

  • High-Quality Data Output: Critical for reliable and accurate treatment decisions.

  • Customizable Workflows: Accommodates specific needs of CMTA studies.

  • Rapid Turnaround Time: Essential for timely results in oncology.

Unlocking the Potential of CMTA with MGI Sequencers

MGI sequencers contribute significantly to the effectiveness of CMTA in precision oncology.

  • Comprehensive Profiling: Integrates exome and transcriptome data for a complete tumor view.

  • Patient-Centric Care: Enables truly personalized treatment strategies.

  • Rare Cancer Research: Facilitates exploration of genetic complexities in rare cancers.

  • Advanced Clinical Trials: Assists in identifying suitable clinical trial candidates.

  • Efficiency and Cost-Effectiveness: Enhances the scope and impact of CMTA studies.

The Future of Precision Oncology

As we stand on the threshold of a new era in oncology, precision medicine promises to reshape the way we approach cancer diagnosis and treatment. Comprehensive Molecular Tumor Analysis (CMTA) is at the forefront of this transformation, and MGI sequencers are pivotal in making it a reality.

The integration of exome sequencing and transcriptome analysis through CMTA, powered by MGI sequencers, holds the potential to provide every cancer patient with tailored treatment options. This approach not only improves therapeutic outcomes but also offers hope to those facing rare and challenging cancers.

In conclusion, the synergy between CMTA and MGI sequencers represents a beacon of hope for patients and a leap forward in the fight against cancer. By embracing the power of genomics and MGI sequencers, we are ushering in a new era of precision oncology where every patient receives the personalized care they deserve.

Disclaimer: The information provided in this blog is for educational and informational purposes only and is not intended for use in diagnostic procedures. MGI products mentioned are for research use only.

DNBSEQ-T7

DNBSEQ-T7

Advancing Personalized Oncology

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Speakers

Dr. Marie-Laure Yaspo - Co-founder and Chief Scientific Officer @ Alacris Theranostics GmbH

Dr. Marie-Laure Yaspo

Co-founder @ Chief Scientific Officer @Alacris

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Priyanka Kurapati - Field Application Scientist @ MGI-tech

Priyanka Kurapati

Field Application Scientist @MGI

Visit Company site

Precision Oncology

Comprehensive Molecular Tumor Analysis

Tumor Microenvironment

DNBSEQ Technology

Exome and Transcriptome Analysis

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Copyright © 2024 MGI tech GmbH, Ltd. All Rights Reserved.

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Copyright © 2024 MGI tech GmbH, Ltd. All Rights Reserved.